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Endonuclease-mediated Allele Detail
Symbol: Cd40lgem1(srta)Vic
Name: CD40 ligand; endonuclease-mediated mutation 1, Gabriel Victora
MGI ID: MGI:6695967
Synonyms: Cd40lgSrtA, Cd40lgSrtA1
Gene: Cd40lg  Location: ChrX:56257503-56269402 bp, + strand  Genetic Position: ChrX, 31.21 cM
Alliance: Cd40lgem1(srta)Vic page
Strain of Origin:  C57BL/6
Allele Type:    Endonuclease-mediated (Epitope tag)
Mutation:    Insertion
Mutation detailsCRISPR-targeting replaced the STOP codon in exon 5 with a floxed stop cassette and the Staphylococcus aureus transpeptidase sortase A (srta) coding sequence. (J:304776)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cd40lg Mutation:  12 strains or lines available
Original:  J:304776 Pasqual G, et al., Monitoring T cell-dendritic cell interactions in vivo by intercellular enzymatic labelling. Nature. 2018 Jan 25;553(7689):496-500
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
MGI 6.22
The Jackson Laboratory