About   Help   FAQ
Alg3tm1e(EUCOMM)Wtsi
Targeted Allele Detail
Summary
Symbol: Alg3tm1e(EUCOMM)Wtsi
Name: ALG3 alpha-1,3- mannosyltransferase; targeted mutation 1e, Wellcome Trust Sanger Institute
MGI ID: MGI:4842439
Gene: Alg3  Location: Chr16:20424208-20429515 bp, - strand  Genetic Position: Chr16, 12.48 cM
IMPC: Alg3 gene page
Mutation
origin
Mutant Cell Lines:  EPD0630_3_B09, EPD0630_3_B12, EPD0630_3_C10, EPD0630_3_C12, EPD0630_3_D10, EPD0630_3_D11, EPD0630_3_D12, EPD0630_3_E09, EPD0630_3_F11, EPD0630_3_G10, EPD0630_3_G11, EPD0630_3_G12
Germline Transmission:  Unknown
Parent Cell Line:  JM8A3.N1 (ES Cell)
Strain of Origin:  C57BL/6N-Atm1Brd
Project Collection: EUCOMM
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutation:    Insertion     Vector: L1L2_Bact_P
 
Mutation detailsThe L1L2_Bact_P cassette was inserted at position 20428297 of Chromosome 16 upstream of the critical exon(s) (Build GRCm39). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by a neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site. Insertion of this cassette creates a reporter knockout mouse. Cre expression will remove the neomycin selection cassette. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml (J:155845, J:173534)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 1 line available
Carrying any Alg3 Mutation:  15 strains or lines available
References
Original:  J:155845 Wellcome Trust Sanger Institute, Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute. MGI Direct Data Submission. 2010;
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
06/12/2024
MGI 6.13
The Jackson Laboratory