Phenotypes Associated with This Genotype

Genotype
MGI:8448938

• Allelic Composition: Slc26a2^em1Zhluo/Slc26a2^em1Zhluo
• Genetic Background: C57BL/6-Slc26a2^em1Zhluo

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

growth/size/body

decreased susceptibility to weight gain ( J:291949 )

• slower weight gain from age 20 weeks onwards

homeostasis/metabolism

homeostasis/metabolism phenotype ( J:291949 )

♂N • normal food intake and intraperitoneal glucose tolerance test result at age 20 weeks

skeleton

skeleton phenotype ( J:291949 )

♂N • normal distal femur bone/trabecular bone volume ratio, bone mineral density, trabecular bone thickness, and trabecular number and spacing at age 2 months

decreased bone mineral density of vertebrae ( J:291949 )

• in the vertebral isthmus at age 11 months

decreased bone mineral density of femur ( J:291949 )

• in distal femur at age 11 months

decreased trabecular bone volume ( J:291949 )

♂ • in distal femur at age 11 months

decreased trabecular bone mass ( J:291949 )

♂ • in distal femur at age 11 months

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
spondylolysis		DOID:2300		J:291949