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Phenotypes Associated with This Genotype
Genotype
MGI:8283264
Allelic
Composition
Hmga2em2Hokl/Hmga2em2Hokl
Genetic
Background
C57BL/6J-Hmga2em2Hokl
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hmga2em2Hokl mutation (0 available); any Hmga2 mutation (12 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
growth/size/body
• mice consistently show a pygmy phenotype

reproductive system
• mice are infertile

adipose tissue
• mouse embryonic fibroblasts (MEFs) show diminished adipogenic differentiation, with reduced lipid droplet formation

cellular
• mouse embryonic fibroblasts (MEFs) show diminished adipogenic differentiation, with reduced lipid droplet formation

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
Silver-Russell syndrome DOID:14681 OMIM:180860
J:348065


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
01/28/2026
MGI 6.24
The Jackson Laboratory