Phenotypes Associated with This Genotype

Genotype
MGI:8283260

• Allelic Composition: Hmga2^em1Hokl/Hmga2^em1Hokl
• Genetic Background: C57BL/6J-Hmga2^em1Hokl

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

growth/size/body

abnormal facial morphology ( J:348065 )

• occasionally, dwarfism is associated with dysmorphic facial features and mainly seen in young mice

decreased body size ( J:348065 )

decreased body weight ( J:348065 )

prenatal growth retardation ( J:348065 )

• small for gestation size

craniofacial

abnormal facial morphology ( J:348065 )

• occasionally, dwarfism is associated with dysmorphic facial features and mainly seen in young mice

adipose tissue

abnormal fat cell differentiation ( J:348065 )

• mouse embryonic fibroblasts (MEFs) show diminished adipogenic differentiation, with reduced lipid droplet formation

cellular

abnormal fat cell differentiation ( J:348065 )

• mouse embryonic fibroblasts (MEFs) show diminished adipogenic differentiation, with reduced lipid droplet formation

reproductive system

reproductive system phenotype ( J:348065 )

N • mice are fertile

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
Silver-Russell syndrome		DOID:14681	OMIM:180860	J:348065