Phenotypes Associated with This Genotype

Genotype
MGI:8270564

• Allelic Composition: Gt(ROSA)26Sor^{tm1(Cacna1c*)Red}/Gt(ROSA)26Sor⁺; Tg(Prrx1-cre)1Cjt/0
• Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL/J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

craniofacial

long mandible ( J:197612 )

• in 6 of 7 mice, the tip of the mandible extends anteriorly as far as, or beyond, the tip of the maxilla

• relatively larger mandible

growth/size/body

long mandible ( J:197612 )

• in 6 of 7 mice, the tip of the mandible extends anteriorly as far as, or beyond, the tip of the maxilla

• relatively larger mandible

skeleton

long mandible ( J:197612 )

• in 6 of 7 mice, the tip of the mandible extends anteriorly as far as, or beyond, the tip of the maxilla

• relatively larger mandible

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
Timothy syndrome		DOID:0060173	OMIM:601005	J:197612