Phenotypes Associated with This Genotype

Genotype
MGI:8250825

• Allelic Composition: F5^em1Alir/F5^em1Alir
• Genetic Background: involves: C57BL/6JOlaHsd * CBA/CaOlaHsd

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

homeostasis/metabolism

abnormal circulating protein level ( J:369439 )

• mice show an increase in Factor V levels

increased bleeding time ( J:369439 )

• mice exhibit lower clotting rates and longer clotting times

• mice exhibit short-duration bleeds during ear tagging

• however, no spontaneous bleeds are seen

increased partial thromboplastin time ( J:369439 )

• activated partial thromboplastin time (aPTT) is increased indicating longer clotting time

increased prothrombin time ( J:369439 )

• prothrombin time (PT) is increased indicating that blood plasma takes longer to clot

mortality/aging

mortality/aging ( J:369439 )

N • no spontaneous deaths are seen

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
factor V deficiency		DOID:2216	OMIM:227400	J:369439