Analysis Tools
cellular
nervous system
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• circulating neurofilament light chain is mildly elevated at 2 months and very elevated at 5 months. Thinly myelinated axons, demyelinated axons, degenerating axons and regenerating axon bundles are found in peripheral nerves at 3 months of age. The femoral nerve is more severely affected than the sensory branch, with proximal ventral roots only mildly affected
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• Thinly myelinated axons, demyelinated axons, degenerating axons and regenerating axon bundles were found in peripheral nerves at approximately 3 months of age. The femoral nerve was more severely affected than the sensory branch, with proximal ventral roots only mildly affected.
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• Nerve conduction velocities of sciatic nerves were found to be reduced by 18 months of age but not 3 or 5 months of age
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Mouse Models of Human Disease |
DO ID | OMIM ID(s) | Ref(s) | |
| Charcot-Marie-Tooth disease X-linked dominant 1 | DOID:0110209 |
OMIM:302800 |
J:369610 | |
