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Phenotypes Associated with This Genotype
Genotype
MGI:7643970
hm1
Allelic
Composition
Tac2em2Ysfk/Tac2em2Ysfk
Genetic
Background
C57BL/6-Tac2em2Ysfk
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tac2em2Ysfk mutation (0 available); any Tac2 mutation (16 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
integument
• mice are less sensitive to IL-31 induced scratching
• however, mice show normal sensitivity to intradermal injection of histamine, chloroquine, or protease-activated receptor 2 agonist (SLIGRL-NH2)-induced scratching


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/30/2025
MGI 6.24
The Jackson Laboratory