Phenotypes Associated with This Genotype

Genotype
MGI:7507073

• Allelic Composition: Cfi^em1Jiwe/Cfi^em1Jiwe
• Genetic Background: involves: C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

renal/urinary system

increased mesangial cell number ( J:308307 )

• mesangial expansion after LPS treatment

homeostasis/metabolism

abnormal complement protein level ( J:308307 )

• significant C3 deposits in mesangium after LPS treatment

immune system

abnormal complement protein level ( J:308307 )

• significant C3 deposits in mesangium after LPS treatment

impaired complement alternative pathway ( J:308307 )

• increased complement activity after LPS treatment

cellular

increased mesangial cell number ( J:308307 )

• mesangial expansion after LPS treatment

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
glomerulonephritis		DOID:2921		J:308307