Phenotypes Associated with This Genotype

Genotype
MGI:7450699

• Allelic Composition: Arpc5^em1.1Mway/Arpc5^em1.1Mway
• Genetic Background: B6J.B6N(C)-Arpc5^em1.1Mway/Mway

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality during organogenesis, incomplete penetrance ( J:334465 )

• mice die between E9.5 and E10.5

embryo

absent pharyngeal arches ( J:334465 )

• absent second arch

failure of initiation of embryo turning ( J:334465 )

incomplete caudal neuropore closure ( J:334465 )

incomplete rostral neuropore closure ( J:334465 )

impaired somite development ( J:334465 )

cardiovascular system

absent cardiac outflow tract ( J:334465 )

craniofacial

absent pharyngeal arches ( J:334465 )

• absent second arch

nervous system

incomplete caudal neuropore closure ( J:334465 )

incomplete rostral neuropore closure ( J:334465 )