About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:6766589
Allelic
Composition		 Hand1tm5Abfi/Hand1+
Tg(Mef2c-cre)2Blk/0
Genetic
Background		 Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hand1tm5Abfi mutation (0 available); any Hand1 mutation (14 available)
Tg(Mef2c-cre)2Blk mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
abnormal cardiac outflow tract development ( J:311466 )
• elongated outflow tract
decreased heart right ventricle size ( J:311466 )
• right ventricle size appears reduced at E14.5 and at P60
• however, mice exhibit a normal left ventricle chamber

Mouse Models of Human Disease
 DO ID OMIM ID(s) Ref(s)
NOT hypoplastic left heart syndrome DOID:9955 OMIM:241550
OMIM:614435
 J:311466

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/09/2024
MGI 6.23 		The Jackson Laboratory