Phenotypes Associated with This Genotype

Genotype
MGI:6477412

• Allelic Composition: Cfap58^em1Fzh/Cfap58^em1Fzh
• Genetic Background: Not Specified

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

reproductive system

reproductive system phenotype ( J:296991 )

♂N • normal testis weight

♂N • normal spermatogonia, spermatocyte, and round spermatid in seminiferous tubules (stages VII and VIII)

coiled sperm flagellum ( J:296991 )

♂ • sperm isolated from cauda epididymis

short sperm flagellum ( J:296991 )

♂ • sperm isolated from cauda epididymis

oligozoospermia ( J:296991 )

♂ • low sperm count in cauda epididymis

abnormal spermatid morphology ( J:296991 )

♂ • absent elongating spermatids with smooth flagella in seminiferous tubules (stages VII and VIII)

asthenozoospermia ( J:296991 )

♂ • sperm isolated from cauda epididymis

immotile sperm ( J:296991 )

♂ • sperm isolated from cauda epididymis

male infertility ( J:296991 )

♂

cellular

coiled sperm flagellum ( J:296991 )

♂ • sperm isolated from cauda epididymis

short sperm flagellum ( J:296991 )

♂ • sperm isolated from cauda epididymis

oligozoospermia ( J:296991 )

♂ • low sperm count in cauda epididymis

abnormal spermatid morphology ( J:296991 )

♂ • absent elongating spermatids with smooth flagella in seminiferous tubules (stages VII and VIII)

asthenozoospermia ( J:296991 )

♂ • sperm isolated from cauda epididymis

immotile sperm ( J:296991 )

♂ • sperm isolated from cauda epididymis

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
oligoasthenoteratozoospermia		DOID:0070311		J:296991