About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:6456819
Allelic
Composition
Mir802em3Gpt/Mir802em3Gpt
Tg(Ins2-cre)25Mgn/0
Genetic
Background
involves: C57BL/6JGpt * DBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mir802em3Gpt mutation (0 available); any Mir802 mutation (2 available)
Tg(Ins2-cre)25Mgn mutation (3 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
homeostasis/metabolism
• in islets from mice fed standard chow or a high-fat diet after glucose stimulation or treatment with 35 mM KCl
• mice fed a high-fat diet exhibit reduced serum insulin concentrations compared with control mice
• after glucose injection or fed a high-fat diet
• in mice challenged with IPGTT or fed a high-fat diet

endocrine/exocrine glands
• increased beta-cell differentiation as determined by marker expression
• in islets from mice fed standard chow or a high-fat diet after glucose stimulation or treatment with 35 mM KCl

cellular
• increased beta-cell differentiation as determined by marker expression


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
03/18/2025
MGI 6.24
The Jackson Laboratory