Phenotypes Associated with This Genotype

Genotype
MGI:6267046

• Allelic Composition: Gt(ROSA)26Sor^{tm1.2(CAG-PLS3,-GFP)Bwir}/Gt(ROSA)26Sor⁺
• Genetic Background: B6N.Cg-Gt(ROSA)26Sor^{tm1.1(CAG-PLS3,-GFP)Bwir}

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

skeleton

decreased osteoclast cell number ( J:267292 )

• at P5, but no at 3M

increased compact bone thickness ( J:267292 )

• in female, but not male, mice

decreased bone trabecula number ( J:267292 )

• however, trabecular bone thickness is normal

increased bone trabecular spacing ( J:267292 )

decreased bone resorption ( J:267292 )

increased bone stiffness ( J:267292 )

• in female, but not male, mice

increased bone strength ( J:267292 )

• in female, but not male, mice

immune system

decreased osteoclast cell number ( J:267292 )

• at P5, but no at 3M

hematopoietic system

decreased osteoclast cell number ( J:267292 )

• at P5, but no at 3M