Phenotypes Associated with This Genotype

Genotype
MGI:5907352

cx2

• Allelic Composition: Lmna^tm1Stw/Lmna⁺; Mlip^{tm1.1(cre)Dzw}/Mlip^{tm1.1(cre)Dzw}
• Genetic Background: involves: 129S1/Sv * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

dilated heart left ventricle ( J:227485 )

• progressive increase in left ventricular internal dimension at end-diastole from 6 to 12 months of age

dilated cardiomyopathy ( J:227485 )

• at 12 months of age

decreased cardiac muscle contractility ( J:227485 )

• progressive decrease in fractional shortening from 6 to 12 months of age

muscle

dilated cardiomyopathy ( J:227485 )

• at 12 months of age

decreased cardiac muscle contractility ( J:227485 )

• progressive decrease in fractional shortening from 6 to 12 months of age