Phenotypes Associated with This Genotype

Genotype
MGI:5907043

cn1

• Allelic Composition: Myocd^tm1Msp/Myocd^tm1Msp
• Genetic Background: involves: 129

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

abnormal myocardial fiber morphology ( J:154666 )

• neonatal primary cardiomyocytes transduced with an adenovirus expressing cre recombinase (Ad-cre) show loss of the loosely arranged myofibrils within 72 hours of Ad-cre infection

cellular

increased cardiomyocyte apoptosis ( J:154666 )

• cardiomyocytes infected with Ad-cre show widespread apoptosis

muscle

abnormal myocardial fiber morphology ( J:154666 )

• neonatal primary cardiomyocytes transduced with an adenovirus expressing cre recombinase (Ad-cre) show loss of the loosely arranged myofibrils within 72 hours of Ad-cre infection

increased cardiomyocyte apoptosis ( J:154666 )

• cardiomyocytes infected with Ad-cre show widespread apoptosis