Phenotypes Associated with This Genotype

Genotype
MGI:5905051

• Allelic Composition: Tg(Myh6-Gnaq*Q209L)44Ejne/0
• Genetic Background: involves: FVB

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

premature death ( J:127756 )

• mice die around 18-19 months of age often with signs of left and right heart failure

cardiovascular system

dilated cardiomyopathy ( J:127756 )

• hemizygous mice develop the same cardiac phenotypes as homozygotes that lead to dilated cardiomyopathy but about 5-6 months later than homozygotes

congestive heart failure ( J:127756 )

• mice show signs of left and right heart failure at 18-19 months of age

muscle

dilated cardiomyopathy ( J:127756 )

• hemizygous mice develop the same cardiac phenotypes as homozygotes that lead to dilated cardiomyopathy but about 5-6 months later than homozygotes

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
dilated cardiomyopathy		DOID:12930	OMIM:PS115200	J:127756