Phenotypes for Zic2 MGI:5827598 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Zic2^Ku/Zic2^Ku
Genetic Background	129S.CAnNCrl(C3)-Zic2^Ku

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Zic2^Ku mutation (4 available); any Zic2 mutation (41 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

embryo

rostral body truncation ( J:238567 )

• embryos have mild anterior truncation and disrupted midline development

• however, they never show entire loss of forebrain or any loss of midbrain

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
holoprosencephaly 5		DOID:0110878	OMIM:609637	J:238567

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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