Phenotypes Associated with This Genotype

Genotype
MGI:5698637

• Allelic Composition: Abcg2^tm1Ahs/Abcg2^tm1Ahs
• Genetic Background: FVB.129P2-Abcg2^tm1Ahs/Tac

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

homeostasis/metabolism

abnormal homeostasis ( J:220924 )

• urate excretion from the intestine is lower

• velocity of intestinal urate excretion is less than half of that in controls

• however, biliary urate excretion is normal

increased blood uric acid level ( J:220924 )

• serum uric acid level is higher

increased urine uric acid level ( J:220924 )

• the urinary urate/creatinine ratio is increased

renal/urinary system

increased urine uric acid level ( J:220924 )

• the urinary urate/creatinine ratio is increased

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
hyperuricemia		DOID:1920		J:220924