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Phenotypes Associated with This Genotype
Genotype
MGI:5646505
cx2
Allelic
Composition		 Clcn2tm1Tjj/Clcn2tm1Tjj
Hepacamtm1.2Tjj/Hepacamtm1.2Tjj
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * C57BL/6NTac
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Clcn2tm1Tjj mutation (0 available); any Clcn2 mutation (39 available)
Hepacamtm1.2Tjj mutation (0 available); any Hepacam mutation (22 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal myelin sheath morphology ( J:210308 )
• myelin vacuolization is increased compared to either single homozygote

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/24/2026
MGI 6.24 		The Jackson Laboratory