Phenotypes Associated with This Genotype

Genotype
MGI:5544605

ht2

• Allelic Composition: Ptch1^dl/Ptch1^tm1Zim
• Genetic Background: involves: 129S1/SvImJ * 129S2/SvPas * C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

Kinked tail, omphalocele, and abnormal skull shape in Ptch1^dl/Ptch1^tm1Zim embryos

craniofacial

domed cranium ( J:204468 )

• domed skull with distinct angular separation from the snout at E18.5

growth/size/body

omphalocele ( J:204468 )

• small at E18.5

abnormal head morphology ( J:204468 )

• domed skull with distinct angular separation from the snout at E18.5

increased fetal size ( J:204468 )

• at E18.5

limbs/digits/tail

kinked tail ( J:204468 )

• at E18.5

skeleton

domed cranium ( J:204468 )

• domed skull with distinct angular separation from the snout at E18.5