About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:5544321
Allelic
Composition		 Furintm1Jwmc/Furintm1Jwmc
Tg(Cd4-cre)1Cwi/0
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6 * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Furintm1Jwmc mutation (0 available); any Furin mutation (49 available)
Tg(Cd4-cre)1Cwi mutation (12 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
abnormal regulatory T cell physiology ( J:204761 )
• regulatory T cells fail to drive Th17 differentiation

immune system
abnormal regulatory T cell physiology ( J:204761 )
• regulatory T cells fail to drive Th17 differentiation

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
08/05/2025
MGI 6.24 		The Jackson Laboratory