Phenotypes for Ampd3 Pklr MGI:5529923 MGI Mouse

About Help FAQ

Phenotypes Associated with This Genotype

Allelic Composition	Ampd3^tm1Tm/Ampd3^tm1Tm Pklr^slc/Pklr^slc
Genetic Background	involves: CBA/NSlc

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ampd3^tm1Tm mutation (0 available); any Ampd3 mutation (39 available)
Pklr^slc mutation (0 available); any Pklr mutation (25 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

growth/size/body

enlarged spleen ( J:203909 )

hematopoietic system

enlarged spleen ( J:203909 )

anemia ( J:203909 )

abnormal erythrocyte morphology ( J:203909 )

reticulocytosis ( J:203909 )

abnormal erythrocyte physiology ( J:203909 )

• ATP, ADP, and AMP levels increase in RBC

increased erythrocyte osmotic fragility ( J:203909 )

• RBC are more fragile under low osmotic conditions

immune system

enlarged spleen ( J:203909 )

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 03/18/2025 MGI 6.24