Phenotypes Associated with This Genotype

Genotype
MGI:5488500

• Allelic Composition: Tlr7^tm1Flv/Y; X/Yaa
• Genetic Background: B6.Cg-Tlr7^tm1Flv Yaa

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

hematopoietic system

hematopoietic system phenotype ( J:127600 )

♂N • spleen marginal zone B cell numbers are similar to wild-type controls

♂N • splenocyte proliferation in response to imiquimod is similar to controls

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
NOT	systemic lupus erythematosus	DOID:9074	OMIM:152700 OMIM:300809 OMIM:605480 OMIM:608437 OMIM:609903 OMIM:609939 OMIM:610065 OMIM:610066 OMIM:612254 OMIM:612378 OMIM:613145 OMIM:614420	J:127600