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Phenotypes Associated with This Genotype
Genotype
MGI:5463447
Allelic
Composition		 b2b1456Clo/b2b1456Clo
Genetic
Background		 C57BL/6J-b2b1456Clo
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
b2b1456Clo mutation (1 available); any b2b1456Clo mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype

Mutant 1456-002-LA has dextrocardia and dextrogastria with inverted liver lobation.

cardiovascular system

growth/size/body
heterotaxia ( J:175213 )
left pulmonary isomerism ( J:175213 )
• left bronchial isomerism
situs inversus totalis ( J:175213 )

respiratory system
left pulmonary isomerism ( J:175213 )
• left bronchial isomerism

Mouse Models of Human Disease
 DO ID OMIM ID(s) Ref(s)
visceral heterotaxy DOID:0050545 OMIM:PS306955
 J:175213

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory