Phenotypes Associated with This Genotype

Genotype
MGI:5445974

• Allelic Composition: Odad3^b2b1885Clo/Odad3^b2b1885Clo
• Genetic Background: C57BL/6J-Odad3^b2b1885Clo

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

Mutant 1885-003-LA displays situs inversus totalis

cardiovascular system

dextrocardia ( J:175213 )

endocrine/exocrine glands

abnormal adrenal gland morphology ( J:175213 )

growth/size/body

situs inversus totalis ( J:175213 )

hematopoietic system

spleen hypoplasia ( J:175213 )

immune system

spleen hypoplasia ( J:175213 )

respiratory system

abnormal respiratory motile cilium physiology ( J:175213 )

• immotile/dyskinetic tracheal airway cilia

immotile respiratory cilia ( J:175213 )

cellular

abnormal respiratory motile cilium physiology ( J:175213 )

• immotile/dyskinetic tracheal airway cilia

immotile respiratory cilia ( J:175213 )

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
Kartagener syndrome		DOID:0050144		J:175213
primary ciliary dyskinesia 30		DOID:0110624	OMIM:616037	J:175213