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Phenotypes Associated with This Genotype
Genotype
MGI:5435246
Allelic
Composition		 Crybb2Lop19/Crybb2+
Genetic
Background		 SJL/J-Crybb2Lop19/BocJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Crybb2Lop19 mutation (1 available); any Crybb2 mutation (11 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
vision/eye
sutural cataract ( J:187061 )
• sutural cataracts are present in heterozygotes by 3 to 4 weeks of age
total cataract ( J:187061 )
• sutural cataracts progress to total lens opacity by approximately 3 months of age

Mouse Models of Human Disease
 DO ID OMIM ID(s) Ref(s)
cataract 3 multiple types DOID:0110269 OMIM:601547
 J:187061

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory