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Phenotypes Associated with This Genotype
Genotype
MGI:5317649
Allelic
Composition
Dnah11b2b1279Clo/Dnah11b2b1279Clo
Genetic
Background
C57BL/6J-Dnah11b2b1279Clo
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dnah11b2b1279Clo mutation (1 available); any Dnah11 mutation (139 available)
phenotype observed in females
phenotype observed in males
N normal phenotype

Mutant 1279-006-1 (E16.5) shows malalignment of the great arteries, which is diagnosed as D-TGA by EFIC imaging

cardiovascular system

growth/size/body

respiratory system
• Airway cilia show a wide range of motion defects including immotility, hyperkinetic beat, dyskinetic and slow cilia motility

cellular
• Airway cilia show a wide range of motion defects including immotility, hyperkinetic beat, dyskinetic and slow cilia motility

craniofacial

muscle

skeleton


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
01/17/2023
MGI 6.22
The Jackson Laboratory