Phenotypes Associated with This Genotype

Genotype
MGI:5306916

• Allelic Composition: Tg(Thy1-GLRA1*R271Q)382Wha/Tg(Thy1-GLRA1*R271Q)382Wha
• Genetic Background: involves: C57BL/6 * DBA/2

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

impaired righting response ( J:76009 )

• onset at ~2 weeks of age

hyperekplexia ( J:76009 )

• onset at ~2 weeks of age

limb grasping ( J:76009 )

• clench hind feet when lifted by the tail from ~2 weeks of age

tremors ( J:76009 )

• exhibit spontaneous and handling-induced 25-30 Hz tremors with onset at ~2 weeks of age

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
hyperekplexia 1		DOID:0060696	OMIM:149400	J:76009