Phenotypes for Oscar MGI:5301434 MGI Mouse

About Help FAQ

Phenotypes Associated with This Genotype

Allelic Composition	Oscar^tm1Ywc/Oscar^tm1Ywc
Genetic Background	involves: 129P2/OlaHsd

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Oscar^tm1Ywc mutation (1 available); any Oscar mutation (25 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

skeleton

abnormal osteoclast differentiation ( J:178250 )

• TGFB1-treated bone marrow macrophage immobilized on a minimal hOSCAR-binding triple-helical peptide (OSC^pep) fail to exhibit an increate in giant TRAP+ osteoclasts unlike similarly treated wild-type cells

cellular

abnormal osteoclast differentiation ( J:178250 )

• TGFB1-treated bone marrow macrophage immobilized on a minimal hOSCAR-binding triple-helical peptide (OSC^pep) fail to exhibit an increate in giant TRAP+ osteoclasts unlike similarly treated wild-type cells

hematopoietic system

abnormal osteoclast differentiation ( J:178250 )

• TGFB1-treated bone marrow macrophage immobilized on a minimal hOSCAR-binding triple-helical peptide (OSC^pep) fail to exhibit an increate in giant TRAP+ osteoclasts unlike similarly treated wild-type cells

immune system

abnormal osteoclast differentiation ( J:178250 )

• TGFB1-treated bone marrow macrophage immobilized on a minimal hOSCAR-binding triple-helical peptide (OSC^pep) fail to exhibit an increate in giant TRAP+ osteoclasts unlike similarly treated wild-type cells

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 03/25/2025 MGI 6.24