Phenotypes for Dock1 MGI:5301324 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Dock1^tm1Jfco/Dock1^tm1Jfco
Genetic Background	involves: 129

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dock1^tm1Jfco mutation (0 available); any Dock1 mutation (130 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

muscle

abnormal myogenesis ( J:178190 )

homeostasis/metabolism

edema ( J:178190 )

• severe edema in a large area of the back at E14.5

cardiovascular system

thick mitral valve cusps ( J:178190 )

• sometimes fused as well

ventricular septal defect ( J:178190 )

• at E14.5

• double outlet at E14.5

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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