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Phenotypes Associated with This Genotype
Genotype
MGI:5298866
ht3
Allelic
Composition		 Esr2tm1Mma/Esr2+
Genetic
Background		 involves: 129S2/SvPas
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Esr2tm1Mma mutation (0 available); any Esr2 mutation (34 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
reproductive system phenotype ( J:105626 )
N
• mice exhibit normal numbers of Sertoli and Leydig cells and level of testicular testosterone production
abnormal germ cell morphology ( J:105626 )
• increased gonocytes after birth with decreased gonocyte apoptosis

cellular
abnormal germ cell morphology ( J:105626 )
• increased gonocytes after birth with decreased gonocyte apoptosis

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/24/2026
MGI 6.24 		The Jackson Laboratory