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Phenotypes Associated with This Genotype
Genotype
MGI:5013602
cn5
Allelic
Composition		 Cop1tm1.1Vmd/Cop1tm2.1Vmd
Tg(CAG-cre/Esr1*)5Amc/0
Genetic
Background		 involves: C57BL/6 * C57BL/6N * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cop1tm1.1Vmd mutation (0 available); any Cop1 mutation (43 available)
Cop1tm2.1Vmd mutation (0 available); any Cop1 mutation (43 available)
Tg(CAG-cre/Esr1*)5Amc mutation (11 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
abnormal prostate gland physiology ( J:172653 )
• xenografted prostate epithelium cells exhibit increased proliferation and form neoplastic prostate structures compared with xenografted wild-type cells

endocrine/exocrine glands
abnormal prostate gland physiology ( J:172653 )
• xenografted prostate epithelium cells exhibit increased proliferation and form neoplastic prostate structures compared with xenografted wild-type cells

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/24/2026
MGI 6.24 		The Jackson Laboratory