Phenotypes Associated with This Genotype

Genotype
MGI:5000281

• Allelic Composition: Tg(AR*100Q)#Als/0
• Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

nervous system

nervous system phenotype ( J:170487 )

N • retrograde transport in motorneurons is normal

motor neuron degeneration ( J:170487 )

• at 18 months, mice exhibit a 40% loss of motorneurons in the sciatic nerve compared with control mice

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
Kennedy's disease		DOID:0060161	OMIM:313200	J:170487