Phenotypes for Fzd9 MGI:4946081 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Fzd9^tm1Uta/Fzd9⁺
Genetic Background	involves: 129X1/SvJ

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fzd9^tm1Uta mutation (1 available); any Fzd9 mutation (36 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

skeleton

decreased bone mineral density ( J:169924 )

• osteopenia

decreased trabecular bone volume ( J:169924 )

decreased compact bone thickness ( J:169924 )

• reduction in cortical thickness of femurs

decreased osteoblast cell number ( J:169924 )

abnormal bone ossification ( J:169924 )

• decrease in bone rate formation

decreased bone strength ( J:169924 )

• vertebral bodies and femora exhibit decreased biomechanical competence

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
Williams-Beuren syndrome		DOID:1928	OMIM:194050	J:169924

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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