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Phenotypes Associated with This Genotype
Genotype
MGI:4847650
ht3
Allelic
Composition		 Tbk1tm1.1Lex/Tbk1+
Genetic
Background		 involves: 129S4/SvJae * 129S5/SvEvBrd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tbk1tm1.1Lex mutation (0 available); any Tbk1 mutation (57 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
abnormal inflammatory response ( J:166476 )
• mice exhibit more cellular infiltrates in multiple organs and tissues compared with wild-type mice that is not as frequent or severe as in homozygous mice

hematopoietic system

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory