Analysis Tools
renal/urinary system
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• urine is much paler than in wild-type mice
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• 1-fold compared to in wild-type mice
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• adult mice exhibit kidney dilation and medulla atrophy unlike in wild-type mice
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• adult mice exhibit renal medulla atrophy unlike in wild-type mice
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• Background Sensitivity: one-third of mice on a mixed 129P2/OlaHsd and C57BL/6 background exhibit overt renal degeneration compared with less than 10% of mice on a pure 129 background which exhibit moderate atrophy
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behavior/neurological
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• female mice drink more water than wild-type mice
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homeostasis/metabolism
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• urine is much paler than in wild-type mice
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• 1-fold compared to in wild-type mice
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