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Phenotypes Associated with This Genotype
Genotype
MGI:4417975
cn4
Allelic
Composition
Hand2tm1Cse/Hand2+
Tg(Hoxb6-cre)#Mku/0
Genetic
Background
involves: 129S1/Sv * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hand2tm1Cse mutation (0 available); any Hand2 mutation (14 available)
Tg(Hoxb6-cre)#Mku mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
N
• embryos are viable to birth

embryo
N
• no visible defects are observed in extraembryonic mesoderm formation

limbs/digits/tail
• mutant neonates exhibit severe limb deformities

cardiovascular system
N
• no visible defects are observed in blood vessel formation


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/24/2026
MGI 6.24
The Jackson Laboratory