About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:4414651
Allelic
Composition		 Ndptm1Lex/Y
Tspan12tm1Wye/Tspan12+
Genetic
Background		 either: (involves: 129S5/SvEvBrd * C57BL/6) or (involves: 129S5/SvEvBrd * FVB/N)
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ndptm1Lex mutation (0 available); any Ndp mutation (7 available)
Tspan12tm1Wye mutation (0 available); any Tspan12 mutation (26 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
vision/eye
abnormal retina vasculature morphology ( J:154863 )
• at P15 and P30, retinal vertical sprouts are reduced compared to in wild-type mice
• retinal vasculature stains positive for a marker of fenestration unlike in wild-type mice

cardiovascular system
abnormal retina vasculature morphology ( J:154863 )
• at P15 and P30, retinal vertical sprouts are reduced compared to in wild-type mice
• retinal vasculature stains positive for a marker of fenestration unlike in wild-type mice

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
01/20/2026
MGI 6.24 		The Jackson Laboratory