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Phenotypes Associated with This Genotype
Genotype
MGI:4397576
Allelic
Composition		 Col10a1tm1.1Rpbh/Col10a1+
Genetic
Background		 involves: 129 * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Col10a1tm1.1Rpbh mutation (0 available); any Col10a1 mutation (29 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype

Growth plate hypertrophic zone expansion in Col10a1tm1.1Rpbh/Col10a1+ and Col10a1tm1.1Rpbh/Col10a1tm1.1Rpbh mice

limbs/digits/tail
short femur ( J:154052 )
• shorter femurs than wild type at 2 and 3 weeks of age

skeleton
short femur ( J:154052 )
• shorter femurs than wild type at 2 and 3 weeks of age
increased width of hypertrophic chondrocyte zone ( J:154052 )
• expanded hypertrophic zones of the growth plates in tibia, femur and ribs at 3 weeks of age
• expanded hypertrophic zones of the growth plates is resolved by 7 weeks of age

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
05/26/2026
MGI 6.24 		The Jackson Laboratory