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Phenotypes Associated with This Genotype
Genotype
MGI:4357974
cx9
Allelic
Composition
Il4tm1Lky/Il4+
Lattm1.1Mal/Lattm1.1Mal
Genetic
Background
involves: 129S2/SvPas * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Il4tm1Lky mutation (3 available); any Il4 mutation (40 available)
Lattm1.1Mal mutation (0 available); any Lat mutation (8 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
immune system
• the first CD4+ T cells that seed the periphery in newborn mice undergo rapid expansion and convert into pathogenic Th2 effector cells

hematopoietic system
• the first CD4+ T cells that seed the periphery in newborn mice undergo rapid expansion and convert into pathogenic Th2 effector cells


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/07/2025
MGI 6.24
The Jackson Laboratory