nervous system
• at 28 days of age there is primary axonal degeneration of the optic nerve, but significant dysmyelination or hypomyelination are not found in the optic nerves at this timepoint
|
vision/eye
• at 28 days of age there is primary axonal degeneration of the optic nerve, but significant dysmyelination or hypomyelination are not found in the optic nerves at this timepoint
|
growth/size/body
• at 28 days of age the average weight of males, 6.3g, is less than half that of normal controls, 14.2g
|
Mouse Models of Human Disease |
DO ID | OMIM ID(s) | Ref(s) | |
cerebellar ataxia, mental retardation and dysequlibrium syndrome | DOID:0050997 |
OMIM:224050 OMIM:610185 OMIM:613227 OMIM:615268 |
J:222308 |