Phenotypes Associated with This Genotype

Genotype
MGI:3832489

cn19

• Allelic Composition: Itga9^tm2Des/Itga9^tm2Des; Tg(KRT14-cre)1Amc/?
• Genetic Background: involves: 129S4/SvJae * C57BL/6 * CBA

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

vision/eye

vision/eye phenotype ( J:144854 )

N • eye size normal

N • corneal clarity normal

abnormal cornea epithelium morphology ( J:144854 )

• basal cells are shorter than in controls and are wider

decreased cornea epithelium thickness ( J:144854 )

• thinner than controls but with a similar number of layers

decreased cornea thickness ( J:144854 )

• cornea is thinner, 50um as compared to 62um

homeostasis/metabolism

abnormal wound healing ( J:144854 )

• reduced proliferation of keratinocytes at 2 and 4 days after wounding

• migration of epithelial cells into the wound area is normal