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Phenotypes Associated with This Genotype
Genotype
MGI:3798308
cx6
Allelic
Composition		 Esr1tm1.1Mma/Esr1tm1.1Mma
Esr2tm1Mma/Esr2+
Genetic
Background		 involves: 129S2/SvPas * C57BL/6 * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Esr1tm1.1Mma mutation (0 available); any Esr1 mutation (72 available)
Esr2tm1Mma mutation (0 available); any Esr2 mutation (34 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
abnormal response/metabolism to endogenous compounds ( J:64426 )
• superovulation induced by gonadotropin treatment is severely reduced compared to in wild-type mice

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/24/2026
MGI 6.24 		The Jackson Laboratory