Phenotypes Associated with This Genotype

Genotype
MGI:3797753

• Allelic Composition: Tg(Eno2-Scn2a1*)Q54Mm/0
• Genetic Background: B6.Cg-Tg(Eno2-Scn2a1*)Q54Mm

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

premature death ( J:136510 )

• 25% of mice are dead by 6 months of age

behavior/neurological

seizures ( J:136510 )

• mice exhibit short partial seizures beginning at 2 months of age

convulsive seizures ( J:170734 )

• mutants exhibit partial motor seizures, however generalized tonic-clonic seizures are rare

nervous system

nervous system phenotype ( J:136510 )

N • mice exhibit normal nervous system morphology

seizures ( J:136510 )

• mice exhibit short partial seizures beginning at 2 months of age

convulsive seizures ( J:170734 )

• mutants exhibit partial motor seizures, however generalized tonic-clonic seizures are rare

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
epilepsy		DOID:1826		J:136510