About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:3795671
Allelic
Composition		 Pkd1tm2Som/Pkd1tm2Som
Tg(Pkhd1-cre)1Igr/0
Genetic
Background		 involves: C57BL/6 * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pkd1tm2Som mutation (0 available); any Pkd1 mutation (153 available)
Tg(Pkhd1-cre)1Igr mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
renal/urinary system
abnormal kidney morphology ( J:135301 )
• at P24, proliferation of the cyst lining cells in the kidney is increased compared to in wild-type mice
increased kidney weight ( J:379194 )
• kidney weight-to-body weight is increased

growth/size/body
kidney cyst ( J:135301 )
polycystic kidney ( J:379194 )
increased kidney weight ( J:379194 )
• kidney weight-to-body weight is increased

Mouse Models of Human Disease
 DO ID OMIM ID(s) Ref(s)
polycystic kidney disease 1 DOID:0110858 OMIM:173900
 J:379194

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/07/2026
MGI 6.24 		The Jackson Laboratory