Phenotypes Associated with This Genotype

Genotype
MGI:3770649

cx6

• Allelic Composition: Lat^tm1.1Mal/Lat^tm1.1Mal; Rag1^tm1Bal/Rag1^tm1Bal
• Genetic Background: involves: 129S2/SvPas * 129S4/SvJae

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

hematopoietic system

decreased platelet aggregation ( J:125744 )

• platelets do not aggregate in response to low doses of a snake venom clotting agonist or collagen

• however, platelets do aggregate in response to low doses of thrombin

abnormal platelet dense granule physiology ( J:125744 )

• platelet-dense granule secretion is absent in response to low doses of the clotting agonist

homeostasis/metabolism

decreased platelet aggregation ( J:125744 )

• platelets do not aggregate in response to low doses of a snake venom clotting agonist or collagen

• however, platelets do aggregate in response to low doses of thrombin

abnormal platelet dense granule physiology ( J:125744 )

• platelet-dense granule secretion is absent in response to low doses of the clotting agonist