Phenotypes for Foxp3 Tg(Cd4-cre)1Cwi MGI:3758965 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Foxp3^tm1Ayr/Foxp3^tm1Ayr Tg(Cd4-cre)1Cwi/?
Genetic Background	involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Foxp3^tm1Ayr mutation (0 available); any Foxp3 mutation (61 available)
Tg(Cd4-cre)1Cwi mutation (12 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

immune system

thymus hypoplasia ( J:125405 )

abnormal T cell differentiation ( J:125405 )

• the number of CD44+CD25- DN1 cells is increased

decreased double-positive T cell number ( J:125405 )

hematopoietic system

thymus hypoplasia ( J:125405 )

abnormal T cell differentiation ( J:125405 )

• the number of CD44+CD25- DN1 cells is increased

decreased double-positive T cell number ( J:125405 )

endocrine/exocrine glands

thymus hypoplasia ( J:125405 )

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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