mortality/aging
|
• most mice die between E12.5 and E14.5
|
nervous system
|
• at E10.5, mice exhibit a failure to close the posterior neural tube
|
exencephaly
(
J:48268
)
vision/eye
|
• at E10.5, mice are missing one or both eyes or display eye abnormalities
|
limbs/digits/tail
polydactyly
(
J:48268
)
|
• mice that survive at E13.5 have extra digits on all four limbs
|
embryo
|
• at E10.5, mice exhibit a failure to close the posterior neural tube
|


Analysis Tools