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Phenotypes Associated with This Genotype
Genotype
MGI:3721245
Allelic
Composition
Rab23opb2/Rab23opb2
Genetic
Background
involves: C3H/HeJ * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rab23opb2 mutation (0 available); any Rab23 mutation (33 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• most mice die between E12.5 and E14.5

nervous system
• at E10.5, mice exhibit a failure to close the posterior neural tube

vision/eye
• at E10.5, mice are missing one or both eyes or display eye abnormalities

limbs/digits/tail
• mice that survive at E13.5 have extra digits on all four limbs

embryo
• at E10.5, mice exhibit a failure to close the posterior neural tube


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/26/2026
MGI 6.24
The Jackson Laboratory